Applications

Automated Metaphases Imaging

Introducing streamlined, reliable, and technologically advanced imaging techniques for detection, segmentation, and user assisted classification of metaphases. Offering cutting-edge tools to simplify and expedite image review and on-screen analysis. With various solutions fitted to the laboratory sample volume, desired automation-level, and integrated web application for both local and remote use, BioView’s products are the ideal solution for your laboratory needs.

The information presented above does not constitute clinical utility. Please refer to the full intended use statement

BioView metaphases imaging review workstation

FISH

Rapid imaging and on-screen review of FFPE sections hybridized with FISH probes as well as matching between parallel tissue sections for targeted analysis.

FFPE tissue section Hybridized with break apart DNA FISH probes

Digital annotation of histology-stained samples and matching with consecutive labelled section

Rapid imaging of fluorescent stained metaphases

Automated imaging and on-screen gallery presentation of cells in suspension, hybridized with FISH probes

Target - FISH

Automated imaging and matching of of multiple stains / markers of the same cell such as Giemsa + FISH, IHC + FISH, IFL +FISH. The platform performs unassisted relocation, automated FISH imaging and side-by-side presentation of the same cells processed using different stains.

Rare cells identified in the peripheral blood were consecutively hybridized with FISH probes.

Giemsa-stained plasma cells consecutively hybridized FISH probes

Cytology samples consecutively stained with Papanicolaou and FISH probes.

Rare cells detection

All-in-one automated platforms for rapid detection, imaging and characterization of rare cells from peripheral blood.

Powered by state-of-the-art imaging algorithms, the platform seamlessly integrates with any sample processing technique. Its sophisticated algorithms automatically detect and characterize rare cells regardless of the cell enrichment method or biomarker used, transforming what was once a manual process into a high-throughput automated workflow.

BioView rare cells detection scanner and review workstation

Custom-fitted to various microfluidic chip and cell filtration devices

Microfluidic chip and cell filtration devices supported by BioView imaging

Designed to support automated imaging of various cell enrichment techniques independent of specific geometric patterns, 3D structures, and materials.

Fully adaptable to all fluorescent markers

Supports imaging & review of any combination of fluorescent markers, Proteins / RNA / DNA FISH, simultaneously or consecutively hybridized.

Co-hybridization of immuno-fluorescent antibodies and FISH

Automated Rare Cell detection

Cells are sorted and classified by combining advanced algorithms with fully adjustable gating criteria including morphology and signal attributes, ensuring precise detection of rare cell events within a sample while maintaining high specificity.

Cells characterization

The combined algorithms and biometric data allows forming assay-specific rare-cells gating criteria as well as assisting in assay development. Biometric data can be seamlessly exported to Excel spread sheet.

Multiplex imaging

Utilizing the system automated cell relocation and capture, allows review of multiple biomarkers stained and imaged in consecutive sessions.

High throughput

Combination of best in class optics and unique imaging algorithms specifically tailored to facilitate rapid 3D capture of all cells within the sample.